miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
21809 5' -57.5 NC_004827.1 + 40403 0.66 0.466597
Target:  5'- uGCCGCGCcagGCUGgCGUGCAAUa-- -3'
miRNA:   3'- uCGGCGUGaa-UGGCgGCGCGUUAgga -5'
21809 5' -57.5 NC_004827.1 + 4295 0.7 0.271658
Target:  5'- cGCCGUaaccuuguugcguuaACUcaccACCGCCGCGCGuuguUCCUu -3'
miRNA:   3'- uCGGCG---------------UGAa---UGGCGGCGCGUu---AGGA- -5'
21809 5' -57.5 NC_004827.1 + 24221 0.72 0.212153
Target:  5'- cGCUGCAUUUAUCGCC-CGCGA-CCa -3'
miRNA:   3'- uCGGCGUGAAUGGCGGcGCGUUaGGa -5'
21809 5' -57.5 NC_004827.1 + 42632 1.07 0.000558
Target:  5'- aAGCCGCACUUACCGCCGCGCAAUCCUc -3'
miRNA:   3'- -UCGGCGUGAAUGGCGGCGCGUUAGGA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.