miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
31618 3' -54 NC_006879.1 + 13253 0.68 0.531543
Target:  5'- gGGCAGaaacagcaUCCGUUACUCCgaGCUgGCa -3'
miRNA:   3'- -CCGUCg-------AGGUAAUGGGGgaUGAaCGc -5'
31618 3' -54 NC_006879.1 + 21434 0.68 0.498518
Target:  5'- gGGCAGCgacgcaUCCugauCCCUCUGCgcUGCGa -3'
miRNA:   3'- -CCGUCG------AGGuaauGGGGGAUGa-ACGC- -5'
31618 3' -54 NC_006879.1 + 2648 0.69 0.46644
Target:  5'- cGGCAGCggCCugUGCCCCUcgcagcucuuaACUUGCGc -3'
miRNA:   3'- -CCGUCGa-GGuaAUGGGGGa----------UGAACGC- -5'
31618 3' -54 NC_006879.1 + 7880 0.7 0.425405
Target:  5'- gGGCAGCUgCGUccCCUCCUGCaacgccUGCGc -3'
miRNA:   3'- -CCGUCGAgGUAauGGGGGAUGa-----ACGC- -5'
31618 3' -54 NC_006879.1 + 22361 1.12 0.000394
Target:  5'- aGGCAGCUCCAUUACCCCCUACUUGCGg -3'
miRNA:   3'- -CCGUCGAGGUAAUGGGGGAUGAACGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.