miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
665 3' -57.2 AC_000018.1 + 2567 0.67 0.434283
Target:  5'- gGCcAGGGgUUGUCGGCAUGGaaGCa -3'
miRNA:   3'- gCGcUCCCgAGCAGUCGUACUggUGg -5'
665 3' -57.2 AC_000018.1 + 28225 0.68 0.405536
Target:  5'- cCGCuaccacccAGGGgUCGUCAGUAgggaGACCGCg -3'
miRNA:   3'- -GCGc-------UCCCgAGCAGUCGUa---CUGGUGg -5'
665 3' -57.2 AC_000018.1 + 24860 0.68 0.378016
Target:  5'- aGCGAGauagcuGCUCGUCA-C-UGACUACCg -3'
miRNA:   3'- gCGCUCc-----CGAGCAGUcGuACUGGUGG- -5'
665 3' -57.2 AC_000018.1 + 18267 0.68 0.369126
Target:  5'- --aGGGGGCUCGUCugcgcGCGUcACCAgCg -3'
miRNA:   3'- gcgCUCCCGAGCAGu----CGUAcUGGUgG- -5'
665 3' -57.2 AC_000018.1 + 16316 0.69 0.343326
Target:  5'- uCGCGGuuGGGCcaUGUUGGCaAUGGCCGCUg -3'
miRNA:   3'- -GCGCU--CCCGa-GCAGUCG-UACUGGUGG- -5'
665 3' -57.2 AC_000018.1 + 8160 1.12 0.000213
Target:  5'- cCGCGAGGGCUCGUCAGCAUGACCACCa -3'
miRNA:   3'- -GCGCUCCCGAGCAGUCGUACUGGUGG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.