miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
9539 5' -54.7 NC_002534.1 + 12792 0.66 0.38359
Target:  5'- aGCUgaAUGUGACCGGuuuUCAACaacauUUCGGUu -3'
miRNA:   3'- -CGGagUACACUGGCC---AGUUG-----AGGCCG- -5'
9539 5' -54.7 NC_002534.1 + 1095 0.67 0.310463
Target:  5'- aGCCaaAUaggGACCGG-CAACUCCaGCa -3'
miRNA:   3'- -CGGagUAca-CUGGCCaGUUGAGGcCG- -5'
9539 5' -54.7 NC_002534.1 + 8805 0.67 0.307938
Target:  5'- gGCCUCAacuugUGUGACuaucaCGGUCAuggccacccucauuGC-CCGGUu -3'
miRNA:   3'- -CGGAGU-----ACACUG-----GCCAGU--------------UGaGGCCG- -5'
9539 5' -54.7 NC_002534.1 + 8006 1.15 6.8e-05
Target:  5'- cGCCUCAUGUGACCGGUCAACUCCGGCa -3'
miRNA:   3'- -CGGAGUACACUGGCCAGUUGAGGCCG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.