miRNA display CGI


Results 1 - 5 of 5 are showing below:
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Acc. No. Name Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
MIMAT0001576 hcmv-miR-UL36 -43.8 NC_006273.1 + 201120 0.68 0.999988
Target:  5'- ----cCCGGGUGUCgcgacaugUCGACGAc -3'
miRNA:   3'- agaaaGGUCCACAGa-------AGUUGCU- -5'
MIMAT0001576 hcmv-miR-UL36 -43.8 NC_006273.1 + 174813 0.69 0.999938
Target:  5'- aUCggUCCcGGUGUCUUCuAugGAg -3'
miRNA:   3'- -AGaaAGGuCCACAGAAG-UugCU- -5'
MIMAT0001576 hcmv-miR-UL36 -43.8 NC_006273.1 + 168040 0.66 1
Target:  5'- ----aCCGGGUGuuucuuuUCUUCAACGGg -3'
miRNA:   3'- agaaaGGUCCAC-------AGAAGUUGCU- -5'
MIMAT0001576 hcmv-miR-UL36 -43.8 NC_006273.1 - 50058 0.9 0.430444
Target:  5'- uUCUUUCCAGGUGUUUUCAACGu -3'
miRNA:   3'- -AGAAAGGUCCACAGAAGUUGCu -5'
MIMAT0001576 hcmv-miR-UL36 -43.8 NC_006273.1 + 49843 1.01 0.123218
Target:  5'- cUCUUUCCAGGUGUCUUCAACGAc -3'
miRNA:   3'- -AGAAAGGUCCACAGAAGUUGCU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.