miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
10262 3' -43.7 NC_002686.1 + 107898 0.67 0.999997
Target:  5'- cUCCgauggUCUUgcUGUugGUGAUGUAGGuGGGg -3'
miRNA:   3'- -AGG-----AGAAauAUA--UACUGUAUCCuCCC- -5'
10262 3' -43.7 NC_002686.1 + 120256 0.67 0.999997
Target:  5'- cUCCgauggUCUUgcUGUugGUGAUGUAGGuGGGg -3'
miRNA:   3'- -AGG-----AGAAauAUA--UACUGUAUCCuCCC- -5'
10262 3' -43.7 NC_002686.1 + 123481 0.69 0.999845
Target:  5'- gUCCUCguccuccUcgGACG-AGGAGGGg -3'
miRNA:   3'- -AGGAGaaauau-AuaCUGUaUCCUCCC- -5'
10262 3' -43.7 NC_002686.1 + 104674 0.69 0.999845
Target:  5'- gUCCUCguccuccUcgGACG-AGGAGGGg -3'
miRNA:   3'- -AGGAGaaauau-AuaCUGUaUCCUCCC- -5'
10262 3' -43.7 NC_002686.1 + 44943 0.86 0.608526
Target:  5'- aCgUUUUUAaugcUAUAUGACAUAGGAGGGg -3'
miRNA:   3'- aGgAGAAAU----AUAUACUGUAUCCUCCC- -5'
10262 3' -43.7 NC_002686.1 + 44753 1.15 0.018803
Target:  5'- uUCCUCUUUAUAUAUGACAUAGGAGGGg -3'
miRNA:   3'- -AGGAGAAAUAUAUACUGUAUCCUCCC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.