miRNA display CGI


Results 41 - 43 of 43 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
10441 3' -52.9 NC_002687.1 + 282707 0.68 0.990108
Target:  5'- cGCGGAGGauagcGGCaGUCUCC---GACGCGg -3'
miRNA:   3'- -CGUCUCU-----CCGcUAGAGGaacUUGCGC- -5'
10441 3' -52.9 NC_002687.1 + 309766 0.71 0.941807
Target:  5'- -uGGAGGGGCGAguuacguauaUCUC-UUGGugGCGg -3'
miRNA:   3'- cgUCUCUCCGCU----------AGAGgAACUugCGC- -5'
10441 3' -52.9 NC_002687.1 + 330566 0.67 0.994146
Target:  5'- --cGAGAacGCGGUugcgCUCCUUGAACGCc -3'
miRNA:   3'- cguCUCUc-CGCUA----GAGGAACUUGCGc -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.