miRNA display CGI


Results 1 - 7 of 7 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
10663 3' -39.5 NC_002730.1 + 10902 0.66 0.999999
Target:  5'- aGGC-GGUGAuuGGUGGAUugcuucuGGAUGAUg -3'
miRNA:   3'- -CUGcCCAUUuuUCACCUAu------UUUAUUA- -5'
10663 3' -39.5 NC_002730.1 + 7955 0.66 0.999998
Target:  5'- uGCGGGaUAuguGAAGUGGAUcccGAUAGc -3'
miRNA:   3'- cUGCCC-AUu--UUUCACCUAuu-UUAUUa -5'
10663 3' -39.5 NC_002730.1 + 37524 0.68 0.999908
Target:  5'- -cCGGGUAAAAAGaUGGcAUAAAuAUAAa -3'
miRNA:   3'- cuGCCCAUUUUUC-ACC-UAUUU-UAUUa -5'
10663 3' -39.5 NC_002730.1 + 4203 0.7 0.999465
Target:  5'- cGCGGGUcgauauauucaGGGAAGUGGGUAuauGUGGc -3'
miRNA:   3'- cUGCCCA-----------UUUUUCACCUAUuu-UAUUa -5'
10663 3' -39.5 NC_002730.1 + 1501 0.71 0.998568
Target:  5'- aAUGGGUAAAAuAGcGGGUAAAAUAu- -3'
miRNA:   3'- cUGCCCAUUUU-UCaCCUAUUUUAUua -5'
10663 3' -39.5 NC_002730.1 + 1204 0.76 0.951691
Target:  5'- cAUGGGUAAAAauccGGUGGGUAAAAUu-- -3'
miRNA:   3'- cUGCCCAUUUU----UCACCUAUUUUAuua -5'
10663 3' -39.5 NC_002730.1 + 1293 1.07 0.044274
Target:  5'- uGACGGGUAAAAAGUGGAUAAAAUAAUu -3'
miRNA:   3'- -CUGCCCAUUUUUCACCUAUUUUAUUA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.