miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
10686 3' -51.3 NC_002766.1 + 2407 0.69 0.184136
Target:  5'- aACaCCCAGucucuGUGGGUacgagucccguAGGCGAuguacGGAACCCc -3'
miRNA:   3'- -UG-GGGUU-----UAUCCA-----------UCUGCU-----CCUUGGG- -5'
10686 3' -51.3 NC_002766.1 + 2186 0.69 0.166757
Target:  5'- uACCCUcGAcAGa-AGGCGAGGAAUCCg -3'
miRNA:   3'- -UGGGGuUUaUCcaUCUGCUCCUUGGG- -5'
10686 3' -51.3 NC_002766.1 + 5303 0.7 0.131815
Target:  5'- aACCCCGGAUauuccaAGGaAGACGuGGcAGCCg -3'
miRNA:   3'- -UGGGGUUUA------UCCaUCUGCuCC-UUGGg -5'
10686 3' -51.3 NC_002766.1 + 4200 1.13 0.000048
Target:  5'- aACCCCAAAUAGGUAGACGAGGAACCCg -3'
miRNA:   3'- -UGGGGUUUAUCCAUCUGCUCCUUGGG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.