miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
1071 5' -58.1 NC_000929.1 + 5640 0.68 0.362295
Target:  5'- aGGGCGGUUGUGGcGACUuUCAguuuuuCCgCCAu -3'
miRNA:   3'- -CCCGCCAGCGCCaUUGAcAGU------GG-GGU- -5'
1071 5' -58.1 NC_000929.1 + 11024 0.68 0.353754
Target:  5'- cGGGgGGUUGUGGcacaGGCUGgacagCACCCg- -3'
miRNA:   3'- -CCCgCCAGCGCCa---UUGACa----GUGGGgu -5'
1071 5' -58.1 NC_000929.1 + 25410 0.7 0.258504
Target:  5'- cGGCGGUCgucguguacggagcgGCGGaAgaauggccccGCUGUUACCCCGc -3'
miRNA:   3'- cCCGCCAG---------------CGCCaU----------UGACAGUGGGGU- -5'
1071 5' -58.1 NC_000929.1 + 19022 0.75 0.119716
Target:  5'- cGGCGGUgGCGGU-GCUGUCugCUg- -3'
miRNA:   3'- cCCGCCAgCGCCAuUGACAGugGGgu -5'
1071 5' -58.1 NC_000929.1 + 29612 1.1 0.000306
Target:  5'- gGGGCGGUCGCGGUAACUGUCACCCCAc -3'
miRNA:   3'- -CCCGCCAGCGCCAUUGACAGUGGGGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.