miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
1078 5' -54.4 NC_000929.1 + 15285 1.05 0.001114
Target:  5'- cACGCUGAUGCAGGCCGUGAUGGAUAUc -3'
miRNA:   3'- -UGCGACUACGUCCGGCACUACCUAUA- -5'
1078 5' -54.4 NC_000929.1 + 3023 0.74 0.202243
Target:  5'- gAUGCUGcgGCAGGCCGUGAa------ -3'
miRNA:   3'- -UGCGACuaCGUCCGGCACUaccuaua -5'
1078 5' -54.4 NC_000929.1 + 30971 0.69 0.401961
Target:  5'- uGCGCUGgcGCAGGCCaucagcgacGUGAUugccacugcggcGGAUGa -3'
miRNA:   3'- -UGCGACuaCGUCCGG---------CACUA------------CCUAUa -5'
1078 5' -54.4 NC_000929.1 + 27256 0.69 0.411757
Target:  5'- cCGCUGGcugUGCcGGuuGUGGUGGAc-- -3'
miRNA:   3'- uGCGACU---ACGuCCggCACUACCUaua -5'
1078 5' -54.4 NC_000929.1 + 26719 0.68 0.462861
Target:  5'- gGCaCUGcgGCGGcaaccGCCGUGAUGGAa-- -3'
miRNA:   3'- -UGcGACuaCGUC-----CGGCACUACCUaua -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.