miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
1092 3' -58.8 NC_000929.1 + 13466 0.68 0.27528
Target:  5'- gGGGuGCCAGCGuGCGCAUCa--UAUCGa -3'
miRNA:   3'- gCCC-CGGUCGU-CGUGUAGacgAUGGC- -5'
1092 3' -58.8 NC_000929.1 + 18377 0.67 0.328469
Target:  5'- gCGGcGGcCCAGCAGCGCAUCgaugACgGc -3'
miRNA:   3'- -GCC-CC-GGUCGUCGUGUAGacgaUGgC- -5'
1092 3' -58.8 NC_000929.1 + 21098 0.67 0.328469
Target:  5'- gCGGGGCCAgaaagagacGguGCACAUCcucauuaguccaUG-UGCCGg -3'
miRNA:   3'- -GCCCCGGU---------CguCGUGUAG------------ACgAUGGC- -5'
1092 3' -58.8 NC_000929.1 + 27217 1.08 0.000273
Target:  5'- gCGGGGCCAGCAGCACAUCUGCUACCGu -3'
miRNA:   3'- -GCCCCGGUCGUCGUGUAGACGAUGGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.