miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
11267 3' -58.1 NC_003059.1 + 7001 0.66 0.135955
Target:  5'- uGGCCCCCAGAacagauaauucaauaUUAUGGacCUGCCaccUGGGc -3'
miRNA:   3'- cCCGGGGGUCU---------------GGUAUU--GACGG---ACCU- -5'
11267 3' -58.1 NC_003059.1 + 6946 0.67 0.110835
Target:  5'- aGGGUgCCCagagAGACCGgagGGCUGUCcaaauUGGAg -3'
miRNA:   3'- -CCCGgGGG----UCUGGUa--UUGACGG-----ACCU- -5'
11267 3' -58.1 NC_003059.1 + 5001 0.68 0.082792
Target:  5'- -uGUCCCCGGGCUgc--CUGUCUGGAa -3'
miRNA:   3'- ccCGGGGGUCUGGuauuGACGGACCU- -5'
11267 3' -58.1 NC_003059.1 + 5312 0.69 0.07755
Target:  5'- gGGGCCCCaCAGACCA--GCUGg--GGc -3'
miRNA:   3'- -CCCGGGG-GUCUGGUauUGACggaCCu -5'
11267 3' -58.1 NC_003059.1 + 4470 1.11 0.00002
Target:  5'- gGGGCCCCCAGACCAUAACUGCCUGGAg -3'
miRNA:   3'- -CCCGGGGGUCUGGUAUUGACGGACCU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.