miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
11473 5' -57.6 NC_003085.1 + 15197 0.66 0.574719
Target:  5'- -cGGUGCgccagCgCCGCGcCGCggaagugggcGAGGUGGAc -3'
miRNA:   3'- cuCCAUGa----G-GGUGCaGCG----------CUCCACCU- -5'
11473 5' -57.6 NC_003085.1 + 16197 0.66 0.574719
Target:  5'- cAGGUACgCUCGCG-CGCGAGGa--- -3'
miRNA:   3'- cUCCAUGaGGGUGCaGCGCUCCaccu -5'
11473 5' -57.6 NC_003085.1 + 21184 0.67 0.528988
Target:  5'- -uGGUACUCgccgcuccacacguCCACGUC-CcAGGUGGAg -3'
miRNA:   3'- cuCCAUGAG--------------GGUGCAGcGcUCCACCU- -5'
11473 5' -57.6 NC_003085.1 + 3647 0.68 0.450912
Target:  5'- aGAGGgacGCUgCaCugGUgGCGAGGuUGGAg -3'
miRNA:   3'- -CUCCa--UGAgG-GugCAgCGCUCC-ACCU- -5'
11473 5' -57.6 NC_003085.1 + 19778 1.08 0.000664
Target:  5'- gGAGGUACUCCCACGUCGCGAGGUGGAc -3'
miRNA:   3'- -CUCCAUGAGGGUGCAGCGCUCCACCU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.