miRNA display CGI


Results 21 - 23 of 23 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
116 5' -55.2 AC_000006.1 + 30533 0.69 0.40116
Target:  5'- aGUCGGGCGAgaccAACggcugcauccacuGCUCCUGCGaaagccccgAGUGUa -3'
miRNA:   3'- -CAGUCCGCU----UUG-------------CGGGGACGU---------UCACG- -5'
116 5' -55.2 AC_000006.1 + 30564 0.68 0.420608
Target:  5'- --uGGGUGAugacuaugggguuGACGCCCaccaUGCAGGUGa -3'
miRNA:   3'- cagUCCGCU-------------UUGCGGGg---ACGUUCACg -5'
116 5' -55.2 AC_000006.1 + 32819 0.79 0.088333
Target:  5'- uGUCGGGCGGGAgGCaCCCUGCuggccGUGUg -3'
miRNA:   3'- -CAGUCCGCUUUgCG-GGGACGuu---CACG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.