miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
11662 3' -51.1 NC_003102.1 + 31897 0.66 0.98545
Target:  5'- gAUGCGGACGGcGGUCcgcUGACUUgGa -3'
miRNA:   3'- -UGUGCCUGCCaUCAGuauACUGAGgU- -5'
11662 3' -51.1 NC_003102.1 + 122840 0.66 0.98545
Target:  5'- -aACGGuACGcGUGGUUGcGUGAUUCCGa -3'
miRNA:   3'- ugUGCC-UGC-CAUCAGUaUACUGAGGU- -5'
11662 3' -51.1 NC_003102.1 + 41988 0.68 0.971461
Target:  5'- aACGgGGACaaauuuaaauGG-AGUCAUAUGACUaCCGu -3'
miRNA:   3'- -UGUgCCUG----------CCaUCAGUAUACUGA-GGU- -5'
11662 3' -51.1 NC_003102.1 + 42171 1.09 0.007943
Target:  5'- gACACGGACGGUAGUCAUAUGACUCCAu -3'
miRNA:   3'- -UGUGCCUGCCAUCAGUAUACUGAGGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.