miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
11736 3' -46.3 NC_003215.1 + 8102 0.66 0.778067
Target:  5'- uUGUUGUCAAAGAUg--GGccggccacuGUCUCCCg -3'
miRNA:   3'- uGCGACAGUUUUUGauaCU---------UAGGGGG- -5'
11736 3' -46.3 NC_003215.1 + 10347 0.67 0.741156
Target:  5'- cCGCUGUCAucGGCc-UGGA-CCCCg -3'
miRNA:   3'- uGCGACAGUuuUUGauACUUaGGGGg -5'
11736 3' -46.3 NC_003215.1 + 9357 0.67 0.715721
Target:  5'- cCGCUGUCAcccauuccucguGAuACUGcGggUCCUCa -3'
miRNA:   3'- uGCGACAGU------------UUuUGAUaCuuAGGGGg -5'
11736 3' -46.3 NC_003215.1 + 10722 0.68 0.689811
Target:  5'- gGCGCUGUCAGgcAAAUUcAUGGagacagggauGUUUCCCa -3'
miRNA:   3'- -UGCGACAGUU--UUUGA-UACU----------UAGGGGG- -5'
11736 3' -46.3 NC_003215.1 + 7012 0.73 0.366543
Target:  5'- gACGCUGUCAugGGCgaaaaa-CCCCCa -3'
miRNA:   3'- -UGCGACAGUuuUUGauacuuaGGGGG- -5'
11736 3' -46.3 NC_003215.1 + 7085 1.15 0.000447
Target:  5'- gACGCUGUCAAAAACUAUGAAUCCCCCa -3'
miRNA:   3'- -UGCGACAGUUUUUGAUACUUAGGGGG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.