miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12112 3' -54.2 NC_003309.1 + 8223 1.12 0.000678
Target:  5'- cCCUGCCACUGGAUCUGUUUGCCCGUCg -3'
miRNA:   3'- -GGACGGUGACCUAGACAAACGGGCAG- -5'
12112 3' -54.2 NC_003309.1 + 19038 0.7 0.525974
Target:  5'- aUCgGCCguuGCUGGAUCUGc--GCgCCGUCg -3'
miRNA:   3'- -GGaCGG---UGACCUAGACaaaCG-GGCAG- -5'
12112 3' -54.2 NC_003309.1 + 23940 0.74 0.310436
Target:  5'- aCUUGaUCGCUGGAcuggacgCUGUcgGCCCGUCg -3'
miRNA:   3'- -GGAC-GGUGACCUa------GACAaaCGGGCAG- -5'
12112 3' -54.2 NC_003309.1 + 24271 0.69 0.591564
Target:  5'- gCCUGCUuCUcGGGUgUGUcgauguaGCCCGUCa -3'
miRNA:   3'- -GGACGGuGA-CCUAgACAaa-----CGGGCAG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.