miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12183 5' -58.1 NC_003309.1 + 18712 0.67 0.469568
Target:  5'- gCCGGCUgcgGCgCGGauACGGCCgCCGa -3'
miRNA:   3'- aGGCCGAaa-UG-GCCcuUGUCGG-GGCa -5'
12183 5' -58.1 NC_003309.1 + 11766 0.7 0.326873
Target:  5'- gUCGGCgcgcCCGGcGAuCAGCCCCGc -3'
miRNA:   3'- aGGCCGaaauGGCC-CUuGUCGGGGCa -5'
12183 5' -58.1 NC_003309.1 + 19637 0.71 0.296604
Target:  5'- cCCGGCcccuucGCCGGGAaccACGGCCCgaCGUu -3'
miRNA:   3'- aGGCCGaaa---UGGCCCU---UGUCGGG--GCA- -5'
12183 5' -58.1 NC_003309.1 + 518 0.72 0.242693
Target:  5'- gCCGGCUc-GCCGGGucgAGCCCCa- -3'
miRNA:   3'- aGGCCGAaaUGGCCCuugUCGGGGca -5'
12183 5' -58.1 NC_003309.1 + 47586 1.07 0.000725
Target:  5'- gUCCGGCUUUACCGGGAACAGCCCCGUc -3'
miRNA:   3'- -AGGCCGAAAUGGCCCUUGUCGGGGCA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.