miRNA display CGI


Results 41 - 42 of 42 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12216 5' -50.7 NC_003309.1 + 43687 0.67 0.903049
Target:  5'- aGCGCGCGcGCCAG-AUCGAaCAcgCc -3'
miRNA:   3'- cCGCGCGCuUGGUUgUAGCU-GUuaGa -5'
12216 5' -50.7 NC_003309.1 + 4183 0.66 0.934266
Target:  5'- aGGCaGCGCGGaugucguccGCCAGC-UCGAacgcgcCGGUCg -3'
miRNA:   3'- -CCG-CGCGCU---------UGGUUGuAGCU------GUUAGa -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.