miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12248 3' -59.9 NC_003309.1 + 29600 0.68 0.285012
Target:  5'- aAACGGUGgauUCgaGCGGCGUGCGgGUCGAUu -3'
miRNA:   3'- -UUGUCGC---AGa-CGCCGCACGU-CGGCUA- -5'
12248 3' -59.9 NC_003309.1 + 13502 0.69 0.263512
Target:  5'- --aGGcCGUCUGCGGCccgcuggGUGUAGCCGu- -3'
miRNA:   3'- uugUC-GCAGACGCCG-------CACGUCGGCua -5'
12248 3' -59.9 NC_003309.1 + 32760 0.69 0.257522
Target:  5'- gGACAGCG-CUGCagcaGGCGUGCGcGCUGu- -3'
miRNA:   3'- -UUGUCGCaGACG----CCGCACGU-CGGCua -5'
12248 3' -59.9 NC_003309.1 + 18540 0.73 0.135452
Target:  5'- ---uGCGcCUGCGaCGUGCAGCCGAa -3'
miRNA:   3'- uuguCGCaGACGCcGCACGUCGGCUa -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.