miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12310 5' -55.7 NC_003323.1 + 6379 1.14 0.000023
Target:  5'- cCCAAGGUCCCAAUUGAGCCCCCAGCCg -3'
miRNA:   3'- -GGUUCCAGGGUUAACUCGGGGGUCGG- -5'
12310 5' -55.7 NC_003323.1 + 733 0.68 0.140003
Target:  5'- -aGAGGugaucgaUCCCGGacGAGCCCCCA-CCu -3'
miRNA:   3'- ggUUCC-------AGGGUUaaCUCGGGGGUcGG- -5'
12310 5' -55.7 NC_003323.1 + 7152 0.66 0.210201
Target:  5'- aCCAcAGGaacaguUCCUGAgauugGAGCCUCCggGGCCa -3'
miRNA:   3'- -GGU-UCC------AGGGUUaa---CUCGGGGG--UCGG- -5'
12310 5' -55.7 NC_003323.1 + 539 0.66 0.210201
Target:  5'- aCAAGGaaguagagaaagUCC----UGGGCCCCguGCCg -3'
miRNA:   3'- gGUUCC------------AGGguuaACUCGGGGguCGG- -5'
12310 5' -55.7 NC_003323.1 + 8755 0.66 0.210201
Target:  5'- aCAAGGaaguagagaaagUCC----UGGGCCCCguGCCg -3'
miRNA:   3'- gGUUCC------------AGGguuaACUCGGGGguCGG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.