miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12359 3' -51.7 NC_003324.1 + 27526 0.66 0.894646
Target:  5'- --aUCCCGAUAGCCccguuGCCUaucaGAUGGc-- -3'
miRNA:   3'- gcaAGGGCUAUCGG-----UGGG----CUACUuuu -5'
12359 3' -51.7 NC_003324.1 + 49322 0.68 0.808749
Target:  5'- aCGggCCCGucgGGCUGCCCGAUc---- -3'
miRNA:   3'- -GCaaGGGCua-UCGGUGGGCUAcuuuu -5'
12359 3' -51.7 NC_003324.1 + 20209 0.69 0.75785
Target:  5'- aCGcgCCCGGUauGGCCggcaGCCCaGAUGGAAu -3'
miRNA:   3'- -GCaaGGGCUA--UCGG----UGGG-CUACUUUu -5'
12359 3' -51.7 NC_003324.1 + 51102 0.69 0.747213
Target:  5'- aCGgUCCCGAUGuaccucGUCACCCGA-GAGGg -3'
miRNA:   3'- -GCaAGGGCUAU------CGGUGGGCUaCUUUu -5'
12359 3' -51.7 NC_003324.1 + 27254 1.07 0.003192
Target:  5'- gCGUUCCCGAUAGCCACCCGAUGAAAAg -3'
miRNA:   3'- -GCAAGGGCUAUCGGUGGGCUACUUUU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.