miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12428 5' -58.9 NC_003324.1 + 18718 0.68 0.399245
Target:  5'- uUUCACUGGcGACGCGCugcGGGuguucucgucGCACAUg -3'
miRNA:   3'- gAGGUGACC-UUGCGCGu--CCC----------CGUGUA- -5'
12428 5' -58.9 NC_003324.1 + 37998 0.68 0.398341
Target:  5'- -gCCAUgccGGAGCgguugcgGCGCAcGGGGCGCGUc -3'
miRNA:   3'- gaGGUGa--CCUUG-------CGCGU-CCCCGUGUA- -5'
12428 5' -58.9 NC_003324.1 + 36543 0.7 0.272039
Target:  5'- aCUCCGauCUGGAACaaGCGCcGcGGGCGCGa -3'
miRNA:   3'- -GAGGU--GACCUUG--CGCGuC-CCCGUGUa -5'
12428 5' -58.9 NC_003324.1 + 10324 0.73 0.192874
Target:  5'- aUCCGCUccuagaaacaguagGGGGCGCGCuGGGGCuCAc -3'
miRNA:   3'- gAGGUGA--------------CCUUGCGCGuCCCCGuGUa -5'
12428 5' -58.9 NC_003324.1 + 11454 1.05 0.000809
Target:  5'- uCUCCACUGGAACGCGCAGGGGCACAUu -3'
miRNA:   3'- -GAGGUGACCUUGCGCGUCCCCGUGUA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.