miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
125 3' -57.1 AC_000006.1 + 11159 1.09 0.000332
Target:  5'- gCCUCUGACGGCGCAGCUGUUCCUGGUg -3'
miRNA:   3'- -GGAGACUGCCGCGUCGACAAGGACCA- -5'
125 3' -57.1 AC_000006.1 + 23628 0.67 0.410615
Target:  5'- gCC-CUGgagcaGCGGCGCAagcucauGCUGgccguggUCCUGGUc -3'
miRNA:   3'- -GGaGAC-----UGCCGCGU-------CGACa------AGGACCA- -5'
125 3' -57.1 AC_000006.1 + 8325 0.66 0.471223
Target:  5'- gCUCccGGCGGCaGCGGCgGUUCC-GGc -3'
miRNA:   3'- gGAGa-CUGCCG-CGUCGaCAAGGaCCa -5'
125 3' -57.1 AC_000006.1 + 13537 0.66 0.502651
Target:  5'- cCCUCguacgagagcgUGAUGGCGCAgGCgac-CCUGGa -3'
miRNA:   3'- -GGAG-----------ACUGCCGCGU-CGacaaGGACCa -5'
125 3' -57.1 AC_000006.1 + 1468 0.66 0.502651
Target:  5'- ---aUGACuaaGCGCAGCUGcgccuaguUUCCUGGg -3'
miRNA:   3'- ggagACUGc--CGCGUCGAC--------AAGGACCa -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.