miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12699 3' -46.5 NC_003349.1 + 99355 0.67 0.999771
Target:  5'- aUGUGUcGCAGUCAAUUGuauGCGAUa---- -3'
miRNA:   3'- -GCACA-UGUCAGUUAAC---CGCUGaaagc -5'
12699 3' -46.5 NC_003349.1 + 11786 0.67 0.999765
Target:  5'- uGUGgcgACAucgCAAUUGGCGACaucacaaUUUCGu -3'
miRNA:   3'- gCACa--UGUca-GUUAACCGCUG-------AAAGC- -5'
12699 3' -46.5 NC_003349.1 + 101186 0.68 0.999267
Target:  5'- -aUGcUACAGUCAucgUGGCGACa---- -3'
miRNA:   3'- gcAC-AUGUCAGUua-ACCGCUGaaagc -5'
12699 3' -46.5 NC_003349.1 + 19234 1.1 0.021122
Target:  5'- uCGUGUACAGUCAAUUGGCGACUUUCGc -3'
miRNA:   3'- -GCACAUGUCAGUUAACCGCUGAAAGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.