miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12719 3' -54.2 NC_003356.1 + 41868 0.66 0.643696
Target:  5'- aUGGUGaa-CGG-GGCGAUUUCGCCCc -3'
miRNA:   3'- -AUCACgagGUCaCUGCUGAAGUGGGu -5'
12719 3' -54.2 NC_003356.1 + 6973 0.67 0.57522
Target:  5'- aGGUGUUCCAGaGGCGuaGCUauucUCugCCAu -3'
miRNA:   3'- aUCACGAGGUCaCUGC--UGA----AGugGGU- -5'
12719 3' -54.2 NC_003356.1 + 18946 0.67 0.57522
Target:  5'- aAGUGCUgaguuauuugagCaaaguaaAGUGAUGAuCUUCACCCAa -3'
miRNA:   3'- aUCACGA------------Gg------UCACUGCU-GAAGUGGGU- -5'
12719 3' -54.2 NC_003356.1 + 16424 0.77 0.147397
Target:  5'- ---cGUUCCAGcguccgGACGGCUUCGCCCAg -3'
miRNA:   3'- aucaCGAGGUCa-----CUGCUGAAGUGGGU- -5'
12719 3' -54.2 NC_003356.1 + 12457 1.07 0.000998
Target:  5'- aUAGUGCUCCAGUGACGACUUCACCCAg -3'
miRNA:   3'- -AUCACGAGGUCACUGCUGAAGUGGGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.