miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12740 3' -58.8 NC_003356.1 + 37266 1.08 0.000317
Target:  5'- cCAGCGCACAAAUCCCCGGGCUGCCACc -3'
miRNA:   3'- -GUCGCGUGUUUAGGGGCCCGACGGUG- -5'
12740 3' -58.8 NC_003356.1 + 29696 0.69 0.25989
Target:  5'- cCAGUGUACAGGUgCCUGuGGUgaauggcgaugaUGCCACu -3'
miRNA:   3'- -GUCGCGUGUUUAgGGGC-CCG------------ACGGUG- -5'
12740 3' -58.8 NC_003356.1 + 40201 0.67 0.359608
Target:  5'- uGGCGCAgGcAUCCCCauguccGGaUGCCACa -3'
miRNA:   3'- gUCGCGUgUuUAGGGGc-----CCgACGGUG- -5'
12740 3' -58.8 NC_003356.1 + 22721 0.66 0.404482
Target:  5'- uGGCGCugAAGUguaUUCCGGG--GCCACa -3'
miRNA:   3'- gUCGCGugUUUA---GGGGCCCgaCGGUG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.