miRNA display CGI


Results 1 - 7 of 7 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
129 3' -58.2 AC_000006.1 + 26810 0.68 0.306172
Target:  5'- --aGCGGCUG-UGCUGCUGUcGGUa- -3'
miRNA:   3'- gagCGCCGACgACGACGACGaCUAgc -5'
129 3' -58.2 AC_000006.1 + 32372 0.69 0.269087
Target:  5'- -cCGgGGCucggUGCgGCUGCUGCaaauggGAUCGg -3'
miRNA:   3'- gaGCgCCG----ACGaCGACGACGa-----CUAGC- -5'
129 3' -58.2 AC_000006.1 + 30381 0.69 0.23571
Target:  5'- uUgGCGGCacGCUcCUGCUGCUGA-CGg -3'
miRNA:   3'- gAgCGCCGa-CGAcGACGACGACUaGC- -5'
129 3' -58.2 AC_000006.1 + 11251 0.7 0.217398
Target:  5'- gUCGCug--GCUGCUGgaGCUGAUCa -3'
miRNA:   3'- gAGCGccgaCGACGACgaCGACUAGc -5'
129 3' -58.2 AC_000006.1 + 3689 0.72 0.164953
Target:  5'- aUgGCGGCUGCgGCUGCcgcgGCUGcggCGg -3'
miRNA:   3'- gAgCGCCGACGaCGACGa---CGACua-GC- -5'
129 3' -58.2 AC_000006.1 + 3742 0.72 0.151588
Target:  5'- --aGgGGCUaCUGCUGCUGCUGggCa -3'
miRNA:   3'- gagCgCCGAcGACGACGACGACuaGc -5'
129 3' -58.2 AC_000006.1 + 12439 1.08 0.000267
Target:  5'- aCUCGCGGCUGCUGCUGCUGCUGAUCGc -3'
miRNA:   3'- -GAGCGCCGACGACGACGACGACUAGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.