miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
13010 5' -54.4 NC_003390.1 + 4925 0.68 0.577759
Target:  5'- uGGAGAGccaUGCgaUAGGCCucuugcuuaGCUGCAGGg -3'
miRNA:   3'- -UCUCUCc--ACGacAUCCGG---------UGAUGUCC- -5'
13010 5' -54.4 NC_003390.1 + 38883 0.68 0.576646
Target:  5'- gGGAGAGGUGCcuUGGaGCCcCUcaaaggcGCGGGa -3'
miRNA:   3'- -UCUCUCCACGacAUC-CGGuGA-------UGUCC- -5'
13010 5' -54.4 NC_003390.1 + 31022 0.69 0.501402
Target:  5'- uGGaAGAGGUGUugggUGUGGGUCAUgaUGCAGu -3'
miRNA:   3'- -UC-UCUCCACG----ACAUCCGGUG--AUGUCc -5'
13010 5' -54.4 NC_003390.1 + 19164 0.7 0.490835
Target:  5'- aAGuGGGGUGCUGaguGGCUccGCUGguGGu -3'
miRNA:   3'- -UCuCUCCACGACau-CCGG--UGAUguCC- -5'
13010 5' -54.4 NC_003390.1 + 3557 1.1 0.000781
Target:  5'- aAGAGAGGUGCUGUAGGCCACUACAGGu -3'
miRNA:   3'- -UCUCUCCACGACAUCCGGUGAUGUCC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.