miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
13588 5' -58.6 NC_003444.1 + 8575 0.66 0.367044
Target:  5'- aGCAGGGUCUGcUGCUcGGUcauCGUGaaCCGUu -3'
miRNA:   3'- aCGUCUCAGAC-ACGA-CCG---GCAC--GGUA- -5'
13588 5' -58.6 NC_003444.1 + 28372 0.68 0.277943
Target:  5'- -uCAGGGUgaGUGCUGGCCcaGCUAUc -3'
miRNA:   3'- acGUCUCAgaCACGACCGGcaCGGUA- -5'
13588 5' -58.6 NC_003444.1 + 5101 0.74 0.104631
Target:  5'- cGCGGcAGUCUGUGUUGuGCCGgucacugaugcUGCCAg -3'
miRNA:   3'- aCGUC-UCAGACACGAC-CGGC-----------ACGGUa -5'
13588 5' -58.6 NC_003444.1 + 36921 0.97 0.001558
Target:  5'- cUGCAG-GUCUGUGCUGGCCGUGCCAUa -3'
miRNA:   3'- -ACGUCuCAGACACGACCGGCACGGUA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.