miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
1513 5' -53 NC_001335.1 + 2820 0.68 0.772885
Target:  5'- gGGAUC-GUCaccagaCCGGgcaucUGGAUcGUGUCGGu -3'
miRNA:   3'- -CCUAGaCAGa-----GGCC-----ACCUA-CACAGCC- -5'
1513 5' -53 NC_001335.1 + 41696 0.7 0.616046
Target:  5'- aGGAUCUugccaucgucacggaGcCUCCacUGGGUGUGUCGGu -3'
miRNA:   3'- -CCUAGA---------------CaGAGGccACCUACACAGCC- -5'
1513 5' -53 NC_001335.1 + 13834 0.72 0.535566
Target:  5'- aGGAUguaagugGcCUCCGGUGGuuucGUGUCGGu -3'
miRNA:   3'- -CCUAga-----CaGAGGCCACCua--CACAGCC- -5'
1513 5' -53 NC_001335.1 + 41633 1.14 0.000963
Target:  5'- uGGAUCUGUCUCCGGUGGAUGUGUCGGg -3'
miRNA:   3'- -CCUAGACAGAGGCCACCUACACAGCC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.