miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
15443 5' -51.5 NC_003930.1 + 7676 0.66 0.496196
Target:  5'- aGUGGGGAUUCAGUGgccACUGcaggUGGCu -3'
miRNA:   3'- gCGCUCCUAGGUCGU---UGACua--ACUGc -5'
15443 5' -51.5 NC_003930.1 + 5556 0.66 0.484386
Target:  5'- -uCGGGGcgCCGGCGgaacggaucccGCUGAUgaugUGACGc -3'
miRNA:   3'- gcGCUCCuaGGUCGU-----------UGACUA----ACUGC- -5'
15443 5' -51.5 NC_003930.1 + 1651 0.66 0.461182
Target:  5'- aCGaCGAGGAggaagCCGGCGACggcaugucUGAUgugGACc -3'
miRNA:   3'- -GC-GCUCCUa----GGUCGUUG--------ACUAa--CUGc -5'
15443 5' -51.5 NC_003930.1 + 11302 0.68 0.374794
Target:  5'- -uCGAGGG-CCAGgAGCgGAUUGGCa -3'
miRNA:   3'- gcGCUCCUaGGUCgUUGaCUAACUGc -5'
15443 5' -51.5 NC_003930.1 + 4732 1.09 0.00031
Target:  5'- cCGCGAGGAUCCAGCAACUGAUUGACGc -3'
miRNA:   3'- -GCGCUCCUAGGUCGUUGACUAACUGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.