miRNA display CGI


Results 21 - 23 of 23 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
1600 5' -56.3 NC_001347.2 + 191259 0.68 0.884705
Target:  5'- -cACGGcGUaaUGCGGGCAGGCGugcGGCa- -3'
miRNA:   3'- gaUGCC-CA--GCGUCCGUCUGCu--UCGac -5'
1600 5' -56.3 NC_001347.2 + 221196 0.67 0.915738
Target:  5'- gUACGGuccUCGCAGGUGGcACGGuAGUUGg -3'
miRNA:   3'- gAUGCCc--AGCGUCCGUC-UGCU-UCGAC- -5'
1600 5' -56.3 NC_001347.2 + 228240 0.69 0.824324
Target:  5'- gUGCGGGUCGUuucGGCG--UGAAGUUGg -3'
miRNA:   3'- gAUGCCCAGCGu--CCGUcuGCUUCGAC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.