miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
16971 5' -51.6 NC_004323.1 + 113988 0.68 0.966507
Target:  5'- uCCGaGUUUGUCGacaaGGAAUCGUCGgUGg -3'
miRNA:   3'- -GGC-CAAGCAGCcc--UCUUAGCAGCaAC- -5'
16971 5' -51.6 NC_004323.1 + 63283 0.67 0.977692
Target:  5'- -aGGUUCGcUGGcGAu-AUCGUCGUUGa -3'
miRNA:   3'- ggCCAAGCaGCC-CUcuUAGCAGCAAC- -5'
16971 5' -51.6 NC_004323.1 + 60304 0.66 0.992583
Target:  5'- aUGGUguaGUCGGGcGuGUCGUUGUUu -3'
miRNA:   3'- gGCCAag-CAGCCCuCuUAGCAGCAAc -5'
16971 5' -51.6 NC_004323.1 + 62079 1.1 0.007353
Target:  5'- uCCGGUUCGUCGGGAGAAUCGUCGUUGu -3'
miRNA:   3'- -GGCCAAGCAGCCCUCUUAGCAGCAAC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.