miRNA display CGI


Results 21 - 23 of 23 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
17278 5' -48.9 NC_004367.1 + 78928 0.72 0.941211
Target:  5'- uUGGCuagCAAuGUCCACUuuucgcuucACCGCAUGCg -3'
miRNA:   3'- -ACUGua-GUUcUAGGUGA---------UGGUGUGCG- -5'
17278 5' -48.9 NC_004367.1 + 860 0.72 0.936207
Target:  5'- cUGA-AUCAGGAUCaa-UGCCGCugGCa -3'
miRNA:   3'- -ACUgUAGUUCUAGgugAUGGUGugCG- -5'
17278 5' -48.9 NC_004367.1 + 41003 1.14 0.006633
Target:  5'- gUGACAUCAAGAUCCACUACCACACGCg -3'
miRNA:   3'- -ACUGUAGUUCUAGGUGAUGGUGUGCG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.