miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
17440 5' -55.8 NC_004453.1 + 13511 0.66 0.503279
Target:  5'- gACGCGaCUgaaGCGGuGGCcgaaGCGGUggccgaaacGGUGGCg -3'
miRNA:   3'- -UGCGC-GA---UGUUuCCG----UGCCA---------CCACCG- -5'
17440 5' -55.8 NC_004453.1 + 22155 0.66 0.503279
Target:  5'- uACGCuCUACAGAGGUcggcgagaguagGCGGUaGaGUaGGCa -3'
miRNA:   3'- -UGCGcGAUGUUUCCG------------UGCCA-C-CA-CCG- -5'
17440 5' -55.8 NC_004453.1 + 33111 0.67 0.481913
Target:  5'- gUGCGCUGCuac-GCAgUGGgagaugGGUGGCg -3'
miRNA:   3'- uGCGCGAUGuuucCGU-GCCa-----CCACCG- -5'
17440 5' -55.8 NC_004453.1 + 17896 0.72 0.234588
Target:  5'- uACGCGagggaaUGgAAauGGGCACGuUGGUGGCg -3'
miRNA:   3'- -UGCGCg-----AUgUU--UCCGUGCcACCACCG- -5'
17440 5' -55.8 NC_004453.1 + 7356 1.1 0.000349
Target:  5'- aACGCGCUACAAAGGCACGGUGGUGGCc -3'
miRNA:   3'- -UGCGCGAUGUUUCCGUGCCACCACCG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.