miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
17971 3' -51.9 NC_004665.1 + 34834 0.66 0.811381
Target:  5'- -aUGGGGcCGACGAUcuGGAGCUgAUUa -3'
miRNA:   3'- gaACCUC-GCUGCUAu-CUUCGGgUAGc -5'
17971 3' -51.9 NC_004665.1 + 6819 0.68 0.704101
Target:  5'- ---aGAGCGGucuCGAUGGAcucAGCCCAgaUCGg -3'
miRNA:   3'- gaacCUCGCU---GCUAUCU---UCGGGU--AGC- -5'
17971 3' -51.9 NC_004665.1 + 20235 0.69 0.623566
Target:  5'- --cGGAGCGA-GGUAGuAGCCC-UUGg -3'
miRNA:   3'- gaaCCUCGCUgCUAUCuUCGGGuAGC- -5'
17971 3' -51.9 NC_004665.1 + 16545 0.7 0.566033
Target:  5'- cCUUGGcAGUGGCGGUuguAGaCCCAUCa -3'
miRNA:   3'- -GAACC-UCGCUGCUAucuUC-GGGUAGc -5'
17971 3' -51.9 NC_004665.1 + 272 0.71 0.525449
Target:  5'- --aGGAG-GACuuacagauagggacaGAUAGggGCCCAUUGa -3'
miRNA:   3'- gaaCCUCgCUG---------------CUAUCuuCGGGUAGC- -5'
17971 3' -51.9 NC_004665.1 + 5309 1.1 0.001092
Target:  5'- cCUUGGAGCGACGAUAGAAGCCCAUCGg -3'
miRNA:   3'- -GAACCUCGCUGCUAUCUUCGGGUAGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.