miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
17976 5' -54.2 NC_004665.1 + 4586 0.66 0.639547
Target:  5'- -aACGaGAAAGCCAUGCa--GGCCGUg -3'
miRNA:   3'- caUGCcUUUUCGGUGCGacgCUGGCA- -5'
17976 5' -54.2 NC_004665.1 + 31119 0.66 0.62809
Target:  5'- -cACGaAGAAGCC-CGUUGCGAggcCCGUu -3'
miRNA:   3'- caUGCcUUUUCGGuGCGACGCU---GGCA- -5'
17976 5' -54.2 NC_004665.1 + 10098 0.66 0.616636
Target:  5'- -aGCGGGAAGGuCUugGaaGCGGCCu- -3'
miRNA:   3'- caUGCCUUUUC-GGugCgaCGCUGGca -5'
17976 5' -54.2 NC_004665.1 + 31046 0.7 0.431422
Target:  5'- --gUGGAGucguagauGCCACGCaugagGCGACCGUu -3'
miRNA:   3'- cauGCCUUuu------CGGUGCGa----CGCUGGCA- -5'
17976 5' -54.2 NC_004665.1 + 9823 1.07 0.001112
Target:  5'- gGUACGGAAAAGCCACGCUGCGACCGUc -3'
miRNA:   3'- -CAUGCCUUUUCGGUGCGACGCUGGCA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.