miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
17982 3' -54.3 NC_004665.1 + 4304 0.68 0.517325
Target:  5'- gCGCCAGUCcgcUGAGCgUaUGACCgAGACc- -3'
miRNA:   3'- -GUGGUCAG---ACUCGgA-ACUGG-UCUGcu -5'
17982 3' -54.3 NC_004665.1 + 8868 0.66 0.664353
Target:  5'- aGCCAGUCaGAGaCCUUGAaggaaGGGCa- -3'
miRNA:   3'- gUGGUCAGaCUC-GGAACUgg---UCUGcu -5'
17982 3' -54.3 NC_004665.1 + 18296 1.08 0.000823
Target:  5'- uCACCAGUCUGAGCCUUGACCAGACGAc -3'
miRNA:   3'- -GUGGUCAGACUCGGAACUGGUCUGCU- -5'
17982 3' -54.3 NC_004665.1 + 25965 0.66 0.618598
Target:  5'- gCACCAaccugCUGcGCUcucugcgUGACCAGACGAu -3'
miRNA:   3'- -GUGGUca---GACuCGGa------ACUGGUCUGCU- -5'
17982 3' -54.3 NC_004665.1 + 27567 0.67 0.595753
Target:  5'- aACCGGgccUCUGGGUCUgGGCCAGuucaccaagGCGAc -3'
miRNA:   3'- gUGGUC---AGACUCGGAaCUGGUC---------UGCU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.