miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
18011 5' -56.7 NC_004665.1 + 19841 0.66 0.538729
Target:  5'- aAGUCGAggcccgagUGGgcgCUUCGAGCuGGUaagGCAc -3'
miRNA:   3'- -UCAGCU--------ACCa--GAGGCUCGuCCAg--CGU- -5'
18011 5' -56.7 NC_004665.1 + 29150 0.66 0.538729
Target:  5'- cAGcUUGuUGGUCUUCggauuGAGCGGGUUGCu -3'
miRNA:   3'- -UC-AGCuACCAGAGG-----CUCGUCCAGCGu -5'
18011 5' -56.7 NC_004665.1 + 2602 0.68 0.424877
Target:  5'- cAGUCGGUGuuga-UGAGCGGGUCGUg -3'
miRNA:   3'- -UCAGCUACcagagGCUCGUCCAGCGu -5'
18011 5' -56.7 NC_004665.1 + 11960 0.96 0.004062
Target:  5'- aAGUCGAUGGUCUCCGA-CAGGUCGCAg -3'
miRNA:   3'- -UCAGCUACCAGAGGCUcGUCCAGCGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.