miRNA display CGI


Results 21 - 25 of 25 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
18437 3' -56.2 NC_004681.1 + 46708 0.7 0.515719
Target:  5'- cGGGgcGGgGUCCUCGGcGAgugggccGGuCUGGGCu -3'
miRNA:   3'- -UCCuuCCgCAGGAGCU-CU-------UC-GACCUG- -5'
18437 3' -56.2 NC_004681.1 + 73578 0.7 0.506498
Target:  5'- cAGGAAcGGCcguguuggcacuGUCCUCGAGGAcaauGgUGGGCa -3'
miRNA:   3'- -UCCUU-CCG------------CAGGAGCUCUU----CgACCUG- -5'
18437 3' -56.2 NC_004681.1 + 51495 0.74 0.31738
Target:  5'- cGGAGGGCacGUUCugcugcaugUCGAGGAGCUGGGg -3'
miRNA:   3'- uCCUUCCG--CAGG---------AGCUCUUCGACCUg -5'
18437 3' -56.2 NC_004681.1 + 10004 0.75 0.274062
Target:  5'- gGGGAAGGCGUCggCcAGcuGCUGGGCg -3'
miRNA:   3'- -UCCUUCCGCAGgaGcUCuuCGACCUG- -5'
18437 3' -56.2 NC_004681.1 + 59317 0.66 0.759788
Target:  5'- gAGGAGcuGaCGUUCU--GGAAGCUGGACg -3'
miRNA:   3'- -UCCUUc-C-GCAGGAgcUCUUCGACCUG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.