miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
20422 5' -51.2 NC_004688.1 + 62020 0.66 0.980314
Target:  5'- -aAGGGGAUGccguGCCGGA-AGUGcUUCCUg -3'
miRNA:   3'- acUUCCUUAU----CGGCCUcUCAC-AAGGA- -5'
20422 5' -51.2 NC_004688.1 + 8619 0.67 0.954991
Target:  5'- gUGGAGGcGUAGCCcucaaggacGAGAGUGUUUUc -3'
miRNA:   3'- -ACUUCCuUAUCGGc--------CUCUCACAAGGa -5'
20422 5' -51.2 NC_004688.1 + 77786 0.68 0.936403
Target:  5'- gUGGAGGcAUgaccGGUCGGAGuGUGggCCg -3'
miRNA:   3'- -ACUUCCuUA----UCGGCCUCuCACaaGGa -5'
20422 5' -51.2 NC_004688.1 + 54421 0.7 0.878977
Target:  5'- cGggGGAA-GGCUGGAGuGGUGgcCCg -3'
miRNA:   3'- aCuuCCUUaUCGGCCUC-UCACaaGGa -5'
20422 5' -51.2 NC_004688.1 + 13834 1.08 0.006425
Target:  5'- gUGAAGGAAUAGCCGGAGAGUGUUCCUc -3'
miRNA:   3'- -ACUUCCUUAUCGGCCUCUCACAAGGA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.