miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
20874 5' -56.6 NC_004689.1 + 7548 0.68 0.618657
Target:  5'- -aGUGCGgcacGCuGGCGUGCGGUcaUCUUCc -3'
miRNA:   3'- agCGCGCa---UGuCCGCACGCUA--AGGGG- -5'
20874 5' -56.6 NC_004689.1 + 37284 0.69 0.555372
Target:  5'- -gGCGCGgucuucGCGGGCuuggGUGCGG-UCUCCg -3'
miRNA:   3'- agCGCGCa-----UGUCCG----CACGCUaAGGGG- -5'
20874 5' -56.6 NC_004689.1 + 36394 0.7 0.514219
Target:  5'- aUCGCGCuUGCAGGCGcagggaauCGcgUCCCa -3'
miRNA:   3'- -AGCGCGcAUGUCCGCac------GCuaAGGGg -5'
20874 5' -56.6 NC_004689.1 + 21721 0.7 0.50412
Target:  5'- gUUGCGgG-GCAGGCGUGUugggagccGGUgCCCCa -3'
miRNA:   3'- -AGCGCgCaUGUCCGCACG--------CUAaGGGG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.