miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
21128 5' -41.6 NC_004775.1 + 6651 0.66 0.999867
Target:  5'- uUGAaUUCGUCAcggUACGCAcgGAACUg -3'
miRNA:   3'- cACUcAAGUAGU---AUGUGUuaUUUGGu -5'
21128 5' -41.6 NC_004775.1 + 36601 0.67 0.999457
Target:  5'- aUGAGUUUgaagAUUAcgGCACgAAUGAACCAg -3'
miRNA:   3'- cACUCAAG----UAGUa-UGUG-UUAUUUGGU- -5'
21128 5' -41.6 NC_004775.1 + 24766 0.86 0.416896
Target:  5'- -gGGGUUCGUUAUGCACAGUAAACg- -3'
miRNA:   3'- caCUCAAGUAGUAUGUGUUAUUUGgu -5'
21128 5' -41.6 NC_004775.1 + 24796 1.11 0.015771
Target:  5'- gGUGAGUUCAUCAUACACAAUAAACCAc -3'
miRNA:   3'- -CACUCAAGUAGUAUGUGUUAUUUGGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.