miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
2146 5' -58.8 NC_001362.1 + 6073 0.67 0.086841
Target:  5'- cGGGGCCCccuuguugcucagGGAgCAGCGGGaacguugcAGGCUg- -3'
miRNA:   3'- aCCCCGGG-------------UCUgGUCGUUU--------UCCGGau -5'
2146 5' -58.8 NC_001362.1 + 2365 0.67 0.087128
Target:  5'- aGGGGUCCAGGauuuugggUCAGCAcggagguuGGGCCc- -3'
miRNA:   3'- aCCCCGGGUCU--------GGUCGUuu------UCCGGau -5'
2146 5' -58.8 NC_001362.1 + 3745 0.68 0.062487
Target:  5'- cUGGGGCCUuggcgucGGCCGGU----GGCCUAc -3'
miRNA:   3'- -ACCCCGGGu------CUGGUCGuuuuCCGGAU- -5'
2146 5' -58.8 NC_001362.1 + 6090 0.73 0.025932
Target:  5'- gGGGGCCCcggGGGCgAGgaaUAGGGGGCCUGa -3'
miRNA:   3'- aCCCCGGG---UCUGgUC---GUUUUCCGGAU- -5'
2146 5' -58.8 NC_001362.1 + 3597 1.06 0.000029
Target:  5'- gUGGGGCCCAGACCAGCAAAAGGCCUAc -3'
miRNA:   3'- -ACCCCGGGUCUGGUCGUUUUCCGGAU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.