miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
21750 5' -65.2 NC_004813.1 + 22489 0.66 0.279379
Target:  5'- gCCGCGGGCaa-CGgUGCGGCuCUGUUa -3'
miRNA:   3'- -GGCGCCCGacgGCgGUGCCG-GACGAc -5'
21750 5' -65.2 NC_004813.1 + 48840 0.66 0.266402
Target:  5'- cCUGUGGGC--CUGCCG-GGCCUGCc- -3'
miRNA:   3'- -GGCGCCCGacGGCGGUgCCGGACGac -5'
21750 5' -65.2 NC_004813.1 + 23812 0.66 0.253916
Target:  5'- aCUGgGGaGuCUGCUGUU-UGGCCUGCUGa -3'
miRNA:   3'- -GGCgCC-C-GACGGCGGuGCCGGACGAC- -5'
21750 5' -65.2 NC_004813.1 + 32569 0.69 0.161748
Target:  5'- uCCGCuuauaGGGUUGCCGCCgguguauGCcGCCggGCUGg -3'
miRNA:   3'- -GGCG-----CCCGACGGCGG-------UGcCGGa-CGAC- -5'
21750 5' -65.2 NC_004813.1 + 38885 1.09 0.000122
Target:  5'- cCCGCGGGCUGCCGCCACGGCCUGCUGa -3'
miRNA:   3'- -GGCGCCCGACGGCGGUGCCGGACGAC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.