miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
21766 3' -57.3 NC_004813.1 + 42733 0.67 0.559252
Target:  5'- aCAGAa-UGCGUUCGUCGUUGCCa-- -3'
miRNA:   3'- aGUCUccACGCGGGCAGUAGCGGaag -5'
21766 3' -57.3 NC_004813.1 + 5673 0.69 0.427543
Target:  5'- uUCA---GUGUGCCCGUC-UgGCCUUCg -3'
miRNA:   3'- -AGUcucCACGCGGGCAGuAgCGGAAG- -5'
21766 3' -57.3 NC_004813.1 + 22272 1.09 0.000639
Target:  5'- aUCAGAGGUGCGCCCGUCAUCGCCUUCc -3'
miRNA:   3'- -AGUCUCCACGCGGGCAGUAGCGGAAG- -5'
21766 3' -57.3 NC_004813.1 + 48293 0.73 0.23383
Target:  5'- gUCAGAGGaUGCGuCCuCGUCcUCGgCUUCu -3'
miRNA:   3'- -AGUCUCC-ACGC-GG-GCAGuAGCgGAAG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.