miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
21822 5' -48.1 NC_004831.2 + 9491 0.66 0.933998
Target:  5'- aGGCU--UGAGUAUUACUucauUGACCCa-- -3'
miRNA:   3'- -UCGGcuAUUCAUAAUGG----ACUGGGaaa -5'
21822 5' -48.1 NC_004831.2 + 12037 0.67 0.908002
Target:  5'- gGGCUGGUAAGU---ACCUGaauaugcgcuGCCCUa- -3'
miRNA:   3'- -UCGGCUAUUCAuaaUGGAC----------UGGGAaa -5'
21822 5' -48.1 NC_004831.2 + 20911 0.69 0.859474
Target:  5'- cAGuuGgGUAAGUAUgcagACCUGACaCCUa- -3'
miRNA:   3'- -UCggC-UAUUCAUAa---UGGACUG-GGAaa -5'
21822 5' -48.1 NC_004831.2 + 7674 0.77 0.413249
Target:  5'- gAGUCGGUAGGUAUUAUCUccacugaaGACCCUa- -3'
miRNA:   3'- -UCGGCUAUUCAUAAUGGA--------CUGGGAaa -5'
21822 5' -48.1 NC_004831.2 + 17501 1.07 0.00488
Target:  5'- cAGCCGAUAAGUAUUACCUGACCCUUUg -3'
miRNA:   3'- -UCGGCUAUUCAUAAUGGACUGGGAAA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.