miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
21920 3' -60.4 NC_004913.1 + 8909 0.7 0.273319
Target:  5'- --cGCuCCCCCUGUucgcccuucUCACCACG-CGGa -3'
miRNA:   3'- aguCGcGGGGGACG---------AGUGGUGCuGCC- -5'
21920 3' -60.4 NC_004913.1 + 9202 0.66 0.460037
Target:  5'- gCAGCGCUgCCUGCcggaccuggcUCuCCACGA-GGu -3'
miRNA:   3'- aGUCGCGGgGGACG----------AGuGGUGCUgCC- -5'
21920 3' -60.4 NC_004913.1 + 19443 0.73 0.169267
Target:  5'- aUCAGC-CCCCCUGCU-GCCAcCGGCa- -3'
miRNA:   3'- -AGUCGcGGGGGACGAgUGGU-GCUGcc -5'
21920 3' -60.4 NC_004913.1 + 26170 0.7 0.280018
Target:  5'- gCGGCGUCUCUUGC-CAaaaaCAUGACGGu -3'
miRNA:   3'- aGUCGCGGGGGACGaGUg---GUGCUGCC- -5'
21920 3' -60.4 NC_004913.1 + 26293 1.1 0.000344
Target:  5'- aUCAGCGCCCCCUGCUCACCACGACGGu -3'
miRNA:   3'- -AGUCGCGGGGGACGAGUGGUGCUGCC- -5'
21920 3' -60.4 NC_004913.1 + 56416 0.69 0.338315
Target:  5'- cCAGCGCgCUCUcCUgGUCACGACGGg -3'
miRNA:   3'- aGUCGCGgGGGAcGAgUGGUGCUGCC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.